Gas Integration by Our Technology
The innovation
Our scientists have developed technologies that modify the molecular structure of water by optimizing the bond angle of the molecules. Through a proprietary process, the reactor induces a high-intensity energy state within the fluid, allowing for the achievement of properties not typically accessible through conventional methods.
As part of our research into improving membrane absorption efficiency, we have focused on the integration of gases into fluids, particularly through the addition of hydrogen or oxygen nanobubbles. In physical chemistry, Henry's Law typically governs this equilibrium, but we have successfully exceeded these thermodynamic limits. Our work focuses on manipulating the physical forces that normally inhibit gas solubilization, specifically surface tension, ionic polarization, and molecular frequency modulation.
Plasma, the fourth state of water
Technically, the term 'gas' refers to a state of matter. In water, free 'gas pockets' do not exist, except in the form of bubbles. When we speak of oxygen or carbon dioxide in water, we are referring to dissolved molecules. Although they exist in a gaseous state under standard temperature and pressure conditions, once dissolved, they form a liquid solution where they are no longer considered gases, but solutes.
As for plasmas, they constitute a highly energetic state of matter where atoms lose their electrons, becoming positively charged ions surrounded by free electrons. This state is so energetic that it is incompatible with the molecular structure of water.
The water
We create new bonds to fix gases where it was previously not possible. Our process achieves concentrations more than 20 times higher than those theoretically established by Henry's Law.
For comparison, conventional bottled water contains approximately 4 ppm (parts per million) of pure oxygen (O2). Through our exclusive reactor, we are able to enrich the water to reach a concentration exceeding 50 ppm of dissolved oxygen!
Proven impact on blood oxygenation during experiments
We have conducted blood oxygenation studies in both canine and human models at Armand-Frappier Santé Biotechnologie Research Centre, a research institute in Canada, yielding exceptional results.https://inrs.ca/en/inrs/research-centres/armand-frappier-sante-biotechnologie-research-centre/
Canine Study Results:
Experimental Protocol: Six Beagle dogs were selected for the study and subjected to CO2 inhalation until the partial pressure of oxygen (PO2) in the blood, measured every 10 minutes, reached a critical survival threshold. This hypoxic condition was maintained across multiple tests over one year.
Administration: Upon reaching the critical survival threshold, the subjects received an intravenous injection of water processed by our technology. This water is characterized by a stable oxygen fixation of 1.8% (18,000 ppm) and a dissolved oxygen concentration of 33 ppm. For each subject and during every trial, the volume was administered via continuous infusion over 60 minutes.
Results: Following the injection, the PO2 levels increased, returning to normal values and stabilizing for nearly 3 hours. Subsequently, metabolic oxygen consumption depleted the available reserves, leading to a rapid decline in PO2. Notably, arterial (PaO2) and venous (PvO2) partial pressures remained similar throughout the experiment.
These tests highlight two fundamental findings:
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Safety and Feasibility of Intravenous Administration: It is safe to intravenously inject water treated with our oxygen nanobubble technology. The administration induced no toxicity or hemodynamic complications in the treated subjects.
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Creation of a Bioavailable Oxygen Reserve: This treated water generates a highly bioavailable oxygen reserve within the blood compartment and tissues. As long as the PO2 remains within normal physiological limits, this stored oxygen is progressively mobilized and consumed by cellular metabolic processes until fully exhausted.
Human Study Results:
A study was conducted on 40 chronic smokers (20 men and 20 women). Placed in a closed, non-ventilated environment, the subjects were exposed to controlled passive smoking throughout the experiment. Each participant ingested 500 ml of water enriched by our technology, ensuring a stable oxygen fixation (1.8% fixed O2 and 100 ppm dissolved O2).
As illustrated below, the subjects' PO2 stabilized, returning to normal physiological values despite the exposure conditions. Subsequently, a progressive decrease in this partial pressure was observed as the bioavailable oxygen reserve was mobilized and consumed to meet tissue metabolic demands.
Nanosight Results
An independent assessment conducted at École Polytechnique de Montréal, using a Malvern Nanosight instrument, was performed to characterize our enriched water. The analysis quantified a concentration of 72 million oxygen nanobubbles per mL, with a mean size of approximately 70 nanometers. This dimension is significantly below the permeability thresholds of the blood-brain barrier and the intestinal barrier, thereby facilitating rapid systemic absorption, a remarkable engineering achievement.
Furthermore, as these nanobubbles are approximately 1,000 times smaller than conventional microbubbles, they significantly reduce effective surface tension and increase gas diffusion to target tissues by a factor of more than 20x.
Additionally, because nanobubbles are roughly 1,000× smaller than conventional micro gas bubbles, they can reduce effective surface tension and increase gas penetration by at least 20x into target tissues.
